Under-Eye Rejuvenation
Say goodbye to hollow, tired-looking eyes without the risks of traditional filler. PDGF (Platelet-Derived Growth Factor) is a breakthrough treatment specifically designed for the delicate under-eye area, where risky filler placement often leads to puffiness or a bluish tint. This pharmaceutical-grade growth factor works both on the surface and deep within your skin—stimulating massive collagen production while visibly improving darkness, hollowness, and thin, crepey texture. Unlike fillers that simply add temporary volume, PDGF harnesses up to 300,000 times more growth factor concentration than traditional treatments to regenerate your skin from within. The result? Smoother, brighter, more youthful under-eyes that look naturally rested and refreshed—never overfilled or puffy.
What is PDGF?
PDGF (Platelet-Derived Growth Factor) is a revolutionary under-eye treatment that uses pharmaceutical-grade, lab-derived growth factors to rejuvenate the delicate under-eye area. Unlike traditional fillers that simply add volume or PRP treatments that require a blood draw, PDGF delivers a pure, sterile concentration of bioidentical growth factors—up to 300,000 times more potent than other aesthetic treatments—to stimulate your body's natural collagen production and cellular regeneration.
PDGF therapy harnesses the regenerative power of growth factors—powerful proteins that signal your body to repair and rebuild tissue. When applied topically with microneedling or precisely injected into the thin, fragile skin under your eyes, PDGF triggers massive collagen and elastin synthesis, improves skin thickness and quality, and gradually restores lost volume from the inside out. Because PDGF is scientifically synthesized under sterile, pharmaceutical conditions and contains no human or animal tissue, you get consistent, predictable results every time—without the variability of blood-based treatments. The result? Brighter, smoother, more youthful-looking eyes that continue improving over time—naturally.
Unlike hyaluronic acid fillers which can create puffiness or a bluish "Tyndall effect" in the delicate under-eye area, PDGF works with your body's biology to create natural, long-lasting improvement without the risk of migration, lumps, or overfilling. No blood draw required. No risk of contamination. Just pure, pharmaceutical-grade regeneration.
Why Choose PDGF?
100% Natural
PDGF is scientifically synthesized under sterile, pharmaceutical conditions - not derived from your blood.
LONG-LASTING RESULTS (12-18+ MONTHS)
Because PDGF builds real tissue rather than adding temporary volume, your results last significantly longer than traditional fillers.
STIMULATES COLLAGEN PRODUCTION
PDGF triggers your body to produce new collagen, elastin, and healthy skin cells—creating improvement that continues developing for months after treatment.
SAFE & BIODEGRADABLE
PDGF is bioidentical to the growth factors your body produces naturally, so it integrates seamlessly into your tissue with minimal risk of complications or adverse reactions.
PDGF Treatment Applications
Regenerate skin from within, heal scars, and reveal naturally radiant results.
PDGF is a revolutionary treatment specifically designed for the delicate under-eye area, where traditional fillers often fail or create unwanted side effects.
Using pharmaceutical-grade platelet-derived growth factor, PDGF interacts directly with stem cells, fibroblasts, and blood vessels beneath the thin under-eye skin to stimulate natural tissue regeneration.
Unlike hyaluronic acid fillers that simply add volume and can cause puffiness, a bluish "Tyndall effect," or migration, PDGF encourages your body to rebuild its own collagen, elastin, and healthy tissue from within.
This approach addresses the root causes of under-eye aging—thin, crepey skin, poor circulation, lost volume, and weakened structural support.
The result is brighter under-eyes with reduced dark circles, smoother texture, diminished hollows, and firmer, more resilient skin that looks naturally refreshed and youthful.
With up to 300,000 times more growth factor concentration than traditional PRP treatments, PDGF delivers consistent, predictable results without requiring a blood draw. Most patients see visible improvement within 3-4 weeks, with continued collagen-building for up to 12 weeks and long-term structural benefits that far outlast temporary fillers.
Is PDGF Right for You?
You're a great candidate if:
You have under-eye hollowing or dark circles.
You want natural, long-lasting results.
You've had issues with filler under eyes (Tyndall effect, puffiness).
You have thin, crepey under-eye skin.
You want to avoid foreign substances.
You're looking for preventative anti-aging.
You have realistic expectations for gradual improvement.
You're not a candidate if:
You're pregnant or breastfeeding.
You have active infection or inflammation in treatment area.
You have blood disorders or clotting issues
You take blood thinners (may need MD clearance).
You want immediate results (PDGF is gradual).
You have unrealistic expectations.
BEFORE & AFTERS
Results you can have faith in
BEFORE
AFTER
REAL PATIENTS. REAL RESULTS.
ALL THE ANSWERS
Frequently Asked Questions
How is PDGF different from PRP?
PDGF offers superior, pharmaceutical-grade growth factor concentration (up to 300,000x higher), consistent results, no blood draw, and predictable outcomes - making it the more advanced, reliable choice for under-eye rejuvenation.
Can PDGF be combined with filler?
Absolutely! PDGF pairs beautifully with other aesthetic treatments to enhance overall skin health and results. It's commonly combined with:
- Microneedling for enhanced collagen stimulation
- Laser treatments (BBL, MOXI, HALO)
- HydraFacials for improved skin quality
- Chemical peels
- Other injectable treatments
Your provider can create a customized treatment plan to address all your under-eye concerns.
Does PDGF hurt?
Most patients find PDGF injections very tolerable. A topical numbing cream is applied before treatment to minimize discomfort at the injection site. During the procedure, you may feel slight pressure or a mild prickling sensation, but the process is generally well-tolerated with minimal pain.
What's the downtime?
Downtime is minimal. Most patients return to normal activities the same day. You may experience mild redness, swelling, or pinpoint bruising at injection sites, which typically resolves within 1-2 days. These side effects are temporary and can easily be covered with makeup after 12-24 hours.
When will I see results?
You may begin to see visible improvement in brightness and texture within 3-4 weeks as collagen production begins. Results continue to develop over the following months, with optimal improvement typically visible at 12 weeks as collagen and elastin production increases. Your under-eye skin will appear firmer, brighter, and more refreshed while fine lines and dark circles gradually fade.
What areas can be treated with PDGF?
PDGF is ideal for addressing:
- Dark circles and discoloration
- Under-eye hollows and volume loss
- Thin, crepey skin beneath the eyes
- Fine lines and wrinkles
- Overall dullness or tired appearance
- Loss of skin firmness and elasticity
How long do PDGF results last?
Because PDGF stimulates your body to produce real collagen and elastin rather than just adding temporary volume, results last significantly longer than traditional fillers. Most patients enjoy results for 6-12+ months, with some experiencing benefits even longer. The structural improvements to your skin continue beyond the initial treatment period.
What should I avoid after treatment?
For the first few days after treatment:
- Avoid touching or rubbing the treated area
- No makeup for 12-24 hours
- Avoid strenuous exercise for 48 hours
- No hot yoga, saunas, steam rooms for 48 hours
- No swimming pools or hot tubs for 48 hours
- Use SPF 50+ and avoid sun exposure
- Avoid active skincare products (retinol, acids) for one week
- Stay well-hydrated
Medical Excellence You Can Trust
All treatments are overseen by our board-certified plastic surgeon
Our carefully assembled team of medical professionals brings together decades of combined experience in aesthetic medicine, reconstructive procedures, and advanced skincare treatments.
Each member of our clinical staff has been selected for their exceptional credentials, specialized training, and unwavering commitment to patient safety. From our board-certified plastic surgeon who oversees all medical procedures to our licensed aesthetic nurses and certified injectors, every provider maintains the highest standards of care and continues their education in the latest techniques and technologies.
Our team approach ensures that every patient receives comprehensive care tailored to their unique goals. Whether you're seeking minimally invasive treatments or more advanced procedures, you can trust that our qualified professionals work collaboratively to deliver natural-looking results with your safety and satisfaction as our top priority.
Regenerate Naturally with Your Body's Healing Power
Serving Spring Hill since 2015 - Hernando County's most trusted medical spa.